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Yest Infection No More

May 9th 2012 at 9:05 PM

Infections caused by Candida species are an important cause of morbidity and mortality and hospitalized medically compromised patients. This work contains the joint recommendations of the German Mycological Society (DMYKG) and the Paul Ehrlich Society for Chemotherapy, Department of Antifungal Chemotherapy (PEG-SAC) for diagnosis and treatment of superficial and invasive Candida infections. They are based on published clinical studies, case series and expert assessment criteria similar to the evidence of the Infectious Diseases Society of America (IDSA). The core thrust of the recommendations are summarized here: The basis of diagnosis remains the detection of microbial pathogens with this identification of Candida species; an in-vitro susceptibility testing is mandatory for all invasive isolates. Choices of initial treatment of candidemia and other invasive Candida infections include patients nichtgranulozytopenischen fluconazole or any of the three approved echinocandins, liposomal amphotericin and voriconazole are subordinate because of unfavorable pharmacological properties alternatives. First-line treatment options for patients granulozytopenischen are mathematically independent because of their fungicidal action, the echinocandins and liposomal amphotericin B. Central venous catheter of the pathogenesis of candidaemia as infectious focus and should be removed whenever possible. Immunosuppressive therapy, mainly by glucocorticoids should, when feasible Yest Infection No More, are sold or at least reduced. The duration of therapy for uncomplicated candidemia is 14 days from the first negative blood culture and complete regression of all infection-associated findings. Before the completion of antifungal chemotherapy fundoscopy to rule out endophthalmitis or chorioretinitis is recommended. About these core statements also contains the detailed operational recommendations on specific organ and systemic infections, the antifungal chemotherapy in pediatric patients as well as an answer precisely discussion of epidemiology, clinical and diagnostic options in development of invasive and superficial Candida infections.

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