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Pressure ulcers - 31 day fat loss cure review
Causes involved in the development of pressure ulcers are diverse. Among these factors are pathophysiological or induced immobility resulting from treatment (13). The mechanisms of action that allow the formation of PU are many. These include pressure, friction, treatments that can produce local ischemia, venous thrombosis and degenerative changes leading to necrosis and ulceration (14).
Between 3 and 12% of patients hospitalized in acute care facilities suffer from some UPP, although these figures reach 40% in high-risk patients and 70% in elderly patients with orthopedic problems. At home, we found an incidence of 4.3% (14). More recent data from 2005, reflected in the 2 nd National Study of Prevalence of pressure ulcers in Spain places us in a few figures mean prevalence of pressure ulcers in hospitalized patients ranges from 3% in surgical units to 22% in care units intensive. In primary care, we found an average prevalence of 9% among those included in the Domiciliary Care program. And in the health centers and residential, the average prevalence is 11% (15).
All health centers, geriatric and residential should have a protocol setting out the main activities to be done to prevent the appearance of new lesions and the progression of existing, or likely to prevent recurrences.
In recent years, essential fatty acids such as linoleic acid, were first used for the prevention and treatment of pressure ulcers (16). Linoleic acid acts as a precursor of arachidonic acid and prostaglandins, both pro-inflammatory mediators, to facilitate the integrity and barrier aqueous epidermal skin.
The largest number of studies found are those that relate hyperoxygenated fatty acids and prevention of pressure ulcers. In all cases the incidence rate decreases after the use of these health products.
Colin et al. have found that topical application of AGHO in the sacral area remained stable TcPO2 values when compared with the control group who had not received any topical agent (P = 0.014) which was observed a decrease of the TcPO2 (17).
In this same kind of pressure sores, studies in the heel area of five healthy volunteers and response variables defined as the difference in blood flow collected via laser Doppler flow meter that measures in real time blood flow tissues. Comparison of the values for a heel vs. AGHO treated. the other untreated check and the same volunteer, resulting in a significant increase in capillary circulation. This increase is achieved very rapidly in time and is stable for a period of time. When performing the same procedure in patients, the results reflect an improvement in blood flow in both heels that they were uninjured and in those who had a grade I pressure ulcers (9).
In a prospective observational study conducted in 36 French nursing homes on a total of 1,121 elderly people at risk of developing pressure ulcers, significant differences between the use of a AGHO and implementation of an oily substance in the prevention of pressure ulcers in sacral (P <0.04), decreasing to about half the relative risk (odds ratio = 0.61) of UPP formation independent of other risk factors (18).
Declair et al. show, in a double-blind comparative study with 86 patients at risk of developing pressure ulcers, the effectiveness of hyper-oxygenated fatty acids in patients with low nutritional status. 31 day fat loss cure review Programs It should also be noted the positive results when assessing hydration and skin elasticity (19). Also, in a clinical trial conducted at the Hospital General Vall d'Hebron with 192 patients showed a statistically significant difference (P <0.007) in the formation of PU. In the control group and experimental applied the usual preventive measures of the center and in the experimental group were used also AGHO (20). They also studied the time it took to receive the UPPs, significantly higher in the experimental group (P <0.025) and relative risk reduction (RRR) was 45.7 (11.8 to 66.6).
Torra et al. (21), in another clinical trial, reported favorable results on the use of hydrogenated fatty acids in terms of reduction in incidence rate (7.32%) when compared with other lipid substances also source as triisostearin (17.32 %) with statistical significance (P = 0.006). This study demonstrates a 58% RRR in applying pressure ulcers vs. AGHO. triisostearin, with the remainder of preventive care was applied to two groups the same. They also concluded that the hydrogenated fatty acids are a much more effective in preventing pressure ulcers using fat creams, presenting an excellent cost / benefit.
In the literature review, we identified only two trials on the use of hydrogenated fatty acids and we have discussed (E. Gallart et al. (20) and Torra et al. (21)). In another recent study of literature review, conducted by A. Lopez et al., refer to these two publications as the only two clinical trials available in the literature that support high evidence (evidence A) use of AGHO in preventing pressure ulcers or, failing that, delay the introduction This type of lesion (12).
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