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New molecules for thrombosis test

Dec 27th 2013 at 8:59 PM

New molecules for thrombosis testTo test blood clotting good candidate Sander van Berkley made new molecules that solve problems with the current test. He also found a way to easily connect complex molecules.for more information about health

Too much blood clotting, thrombosis is at the basis of brain hemorrhage, myocardial infarction, pulmonary embolism, and is thus indirectly a major cause of death. Too little clotting is again dangerous. Good test for blood clotting are therefore of great importance. Thrombin In the process of blood coagulation enzyme thrombin plays an important role.

The activity of this enzyme in the time gives a good picture of the clotting behavior of the blood, and immediately gives a picture of the risk of thrombosis development. In order to determine the activity of thrombin a molecule is needed which selectively reacts with thrombin, and that is easily detectable once the reaction has taken place. This can be done by choosing a fluorescent fragment cleaves a molecule. The fluorescence intensity is a measure of the activity of thrombin. read for more details visit my web pageĀ

Develop new molecules In the current thrombin generation assay, a molecule is used which is not only poorly soluble in water, but also not selective for thrombin: this molecule, namely, also reacts with thrombin which is rendered inactive. by another enzyme Through calculations, then the appropriate thrombin can be determined

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