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marilynaliza | healthiswealth

Multiple sclerosis related to hormonal contraception

Jun 25th 2014 at 9:12 PM

"Regardless of age, smoking, and birth weight, there is a link between the use of hormonal oral contraception and the appearance of the first symptoms of multiple sclerosis," said study author Dr.. Kerstin Hellwig from Kaiser Permanente Southern California. "The results show that taking hormonal contraceptives may be affected by the increase in the incidence of multiple sclerosis among women."

The survey results will be presented at the 66th Annual Congress of the American Academy of Neurologists (AAN), which will be held in late May in Philadelphia.

Research scientists are conducted in a population study in the medical center of Kaiser Permanente Southern California. In the years 2008 to 2011 identified 305 women with a first diagnosis of multiple sclerosis or clinical isolated syndrome.

For each patient with a diagnosis of the selected ten random candidate of a certain age, race and other characteristics.

Data were collected from electronic medical records to a patient, and with the aid of physical logistic regression also analyzed. Corrected the data on smoking and deliveries within three years of the first symptoms.

The results suggest the use of hormonal contraception for at least three months within three years from the onset of symptoms of the disease: 29.2% female patients with multiple sclerosis and 23.5% of candidates in the control group. Most user has been taking estrogen-progesterone combination preparations.

Women who are within three years before the onset of symptoms used hormonal contraception had a 35% higher risk of developing multiple sclerosis and clinical isolated syndrome. In female patients who stopped taking hormonal contraceptives for one month prior to the onset of symptoms, was higher risk by 50%.

Dr. Hellwigova says: "The effect is small and on the basis of this research can not prescribe recommendations. The survey found only a fraction of the whole picture. "It should be noted that two previous studies have shown a similar effect.

Multiple sclerosis in women occur fairly often, some studies have shown the incidence of growth only in females, which raised the issue of whether the way of life of women also explain this difference.

"Hormones are responsible for many diseases, it is well known that pregnancy is associated with high levels of estrogen, which acts preventively and reduces the symptoms of multiple sclerosis, which means that the involvement of the hormones in a way that induces the disease."

One of the assumptions is that low estrogen stimulate autoimmune diseases, but so far there is not enough information about the possible preventive or adverse effect.

Scientists have not determined other factors that may be associated with the lifestyle of women, such as. diet, physical activity or the length of time spent outdoors, so it can still be a number of other potential cofactors.

In the next stage of planning a survey of the whole aspect of life.    

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