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Hematology test provides the chance to die

May 19th 2014 at 10:07 PM

Finns and Estonians scientists claim to have developed a hematology test that can predict how many chances someone has to live or die in the next five years for health reasons, even though it now looks healthy. Researchers, led by Krista Fischer Estonian University Tartu and Johannes Ketounen Institute of Molecular Medicine,

Helsinki, made ​​after publication in the medical journal "PLoS Medicine", took blood samples from 17,345 generally healthy people. They analyzed the samples for more than 100 biomarkers and simultaneously monitored the health of participants for five years, during which 684 died of various diseases. Scientists found that those

who died had similar levels in four specific biomarkers: albumin, the alpha-1 acid glycoprotein, citric acid and the size of the particles of very low density lipoproteins. This, according to the researchers, is somehow the 'signature' of the future death, which can occur from a variety of diseases, such as cancer or heart disease.

Only 20% of those who had the highest levels of these four biomarkers, died within the first time. These biomarkers are mainly related to the functioning of the liver and kidneys, chronic inflammation and infections, energy metabolism and health of blood vessels.

Researchers are now trying to study if there is a "thread" that connects those four ominous biomarkers. "We believe that in the future these tests could be used to identify people who seem healthy but really are serious illnesses that require treatment.

But more studies are needed before these findings make it possible to apply in clinical practice, "said Johannes Ketounen. Estonians scientists first found the "biomarkers of death 'in sample 9,842 people and wanted to make sure, they asked the Finnish researchers to resume

experiment other 7,503 people as Google - with similar results. Professor Markus Perola Health Institute of Finland said that they did not expect to reach the same findings with Estonian. "At first I thought so.

It was amazing that these biomarkers looked really predict the death regardless of ailments, "he said. "But there's a moral question," he added. "Would someone want to know the risk faced die, if not yprchei something we can do about it?"

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