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marilynaliza | healthiswealth

Cord blood - what awaits us in the future

Jun 29th 2014 at 7:25 PM

The Foundation Parent's Guide to Cord Blood (Parental Guide for cord blood) is the only organization, which maintains a database of both public and private cord blood banks. Website since 1998 provides parents with accurate medical information on the possibilities of storing umbilical cord blood.

The founder, Dr. Frances verter is a mother who has lost a child due to cancer, as well as a scientist who investigates and publishes on the topic of storing stem cells from umbilical cord blood.

Website Parent's Guide to Cord Blood is dedicated to the memory of your daughter Shai. Finding a bone marrow donor is in her last very long. Do you think that the situation is now that we have a lot of stored umbilical cord blood, much better than 13 years ago?
When Shai need a stem cell transplant , we have long months around the world looking for a bone marrow donor, as her parents we come from different ethnic groups. When doctors try to "harmonize" the donor with the patient, reviewed 6 types of tissue, called HLA types . These types of human inherited from both parents,

so it is logical that people who have a similar background as the patient, probably corresponding donors. However, when the patient has a mixed background, it is sometimes extremely difficult to find a suitable donor.

This is in some countries is becoming increasingly important as it is, for example, in the U.S. the fastest-growing ethnic group of people who are "mixed race". Most members of this group is today still a child, and thus too young to be able to donate their bone marrow to other patients

of mixed race. reliance on cord blood transplants by removing the barriers of many patients, it is not necessary to such a high correlation as in the bone marrow.

Published medical studies have demonstrated that 4 out of 6 matches in cord blood show the same good results as the transplantation of 6 6 in the bone marrow. If early as 1997, when Shai need a donor, there were growing base of umbilical cord blood, might quickly find a donor and could go on for months before transplantation.

Shai had leukemia and received a lot of chemotherapy, which maintained the disease at rest, when we were looking for a donor. If you find a donor quickly and could go for a transplant as soon as the disease is brought to rest, might have survived.

But no one knows for sure what would have happened in the past.

Have you received any feedback on how this site affects the decisions people to donate their bone marrow or cord blood stored?

Yes, parents, we often write to them, the site is a great help. Occasionally we also get some gratitude to doctors, such as this:

"Thank you, thank you, thank you! I am a gynecologist from Scottsdalea in Arizona and is fascinated by storing stem cells. Today I came across your website and I can not wait to it I will share with their patients. Here is all in one place.

Everything you need to know. You can not imagine how many times I talked about the value of storing stem cells from their patients, and then by their pediatricians or family physicians dissuaded from this idea. Thank you very much for this excellent source of information. "

How many visitors to the site per month? Do many people give their contact information? Do you often receive requests or encouraging thoughts?

On average, our website lists half a million clicks per month. Many clicks are coming from search engines or by parents who read many pages when researching this topic. Number of individual visitors is between 25 and 30 thousand per month

. These visitors come from some 90 different countries. Clearly, the majority of our visitors are from the U.S. and Canada, but we have a lot of visitors from other English-speaking countries, but also from many European and Asian countries, where people good command of the English language.

You become an expert in stem cell transplant and you have decided to save the cord blood of their daughters later. What is your vision storage of umbilical cord blood in the future?
My daughter Shai survived the "successful" transplant in the sense that the stem cell donor "arrested". However, the leukemia returned and Shai has died in September 1997


. In October of the same year I became pregnant again. In this baby, I began to explore storing cord blood website, we launched in summer 1998. Myself, I saved the cord blood of my second and third daughters, who were born in the years 1998 and 2000. I chose a private bank stem cells. When you think about the future

the possibility of storing umbilical cord blood, I see in the near future, the increasing need for public and private banks, long-term, I believe that public banks fail, private but survived. Currently, the number of patients receiving

stem cell transplantation, is increasing, and a growing need for public banks. Public banks looking for donors to patients who do not have a suitable donor within the family. In the U.S., the register of donors in private banks lead NMDP. Predict that, by 2015, a year find a donor for 10,000. More than half of their transplant patient and donor covers from different countries, suggesting that transplantation of international medical undertaking. , however, I think it will be somewhat more distant future stem cell transplantation replaced by targeted medicines for cancer. Treatment of cancer with transplantation as a garden weed suppression with poison - poison kills everything in its path, so the weeds as well as vegetables. Chemotherapy, for use in the transplantation of stem cells, is highly toxic, and many patients die from the side-effects and / or complications. If we had better medicines for cancer that attack only cancer cells, all patients switched to this therapy, stem cell transplant would be considered outdated and barbaric. Therefore, it seems to me that the habit of storing stem cells for transplantation in cancer patients eventually dropped, but is still invaluable for a small number of children each year are born with metabolic disorders. I myself am very confident in this scenario, but I can not predict when this will happen. I wonder if this will continue for the time of my life. During the past 3 years, the use of private cord blood stored in the "regenerative" medicine is growing rapidly. Together with dr. Nietfeldom from the Netherlands, we published a poster at the meeting of the International Society for Cell Therapy (ISCT). The term "regenerative" Medical describes any therapy in which stem cells help the body to be cured. Currently, the regenerative treatment with umbilical cord blood is used most in children who were born with brain damage, or in the early years of developing diabetes. Adult patients receiving regenerative stem cell treatment in the event of a heart attack, spinal cord injuries and autoimmune diseases. However, today, adult people do not have their own stored umbilical cord blood, so this study using stem cells from the patient's bone marrow. In the life science community almost all believe that regenerative medicine is the wave of the future, the main debate is running on which source of stem cells will prevail. I think it will be used to store cord blood as a source of cells for regenerative medicine within the child's family.

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