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Black Raspberries *PM and Remedy Against Colorectal Cancer! The Article

Nov 14th 2010 at 4:22 PM

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Amanda Chan
MyHealthNewsDaily Staff Writer Amanda Chan

myhealthnewsdaily Staff Writer – Tue Nov 2, 2:02 pm ET

Compounds found in black raspberries are effective in preventing colorectal cancer tumors in mice, according to a new study.

The fruits contain compounds called anthocyanins, which give them their color, along with a host of other cancer-fighting vitamins, minerals and acids, said study researcher Gary Stoner, a professor at the College of Medicine at the Ohio State University.

"Due to the high levels of these compounds, the berries have high antioxidant activity," Stoner told MyHealthNewsDaily. He added that it makes them effective in destroying toxic free radicals in the body, which can damage DNA in cells.

If the same result is found in humans, the fruit could be used to help prevent colorectal cancer. Previous studies have found black raspberries - which are different from blackberries - to play a role in preventing esophageal, oral and skin cancers, he said.

Ripe results

Researchers genetically engineered two types of mice to test the benefits of black raspberries. One type was engineered to develop intestinal tumors, and the other type was engineered to have colitis, an inflammation of the large intestine that can lead to colorectal cancer.

For 12 weeks, all mice were fed a "high-risk" diet - which was high in fat and low in calcium and vitamin D - and some were also given a supplement, so 10 percent of their calories came from freeze-dried black raspberry powder.

Both types of mice that ate the black raspberry powder had fewer tumors than the mice not given the supplements.

Among mice engineered to have intestinal tumors, the growth of new tumors decreased by 45 percent, and the total number of tumors in the mice decreased by 60 percent, the study said. The black raspberries stopped tumors from developing by suppressing a protein that binds to the gene that the scientists genetically modified in the mice, the researchers said.

In the mice engineered to have the intestinal inflammation, new tumors and number of tumors were reduced by 50 percent, because the black raspberries worked to reduce inflammation, according to the study.

To get the equivalent of the supplements the researchers gave the mice, a human would have to eat four cups of fresh berries a day, said study researcher Dr. Wancai Yang, an assistant professor at the University of Illinois at Chicago.

That's a lot for humans, but the animals used in the study were engineered to be susceptible to cancer. So for humans, "it is not necessary to eat so much fresh berries to have similar benefit of cancer prevention," he said.

Findings for fruit

Other berries, such as blueberries and strawberries, are also known to have cancer-preventing effects, but their effects are not as great as those of black raspberries, Yang said.

A 2001 study by Stoner in the journal Carcinogenesis found freeze-dried berries stopped the changes that take place cells and lead to cancer. The study used animal cells grown in lab dishes.

And two 2009 studies - one conducted in cells in lab dishes and one conducted in mice - found that compounds in black raspberries can prevent and stop proliferation of esophageal tumor cells. The studies were published in the journals Nutrition and Cancer and Cancer Prevention Research.

Because the black raspberries were shown to lower inflammation, it's possible that they can also protect against other diseases, such as heart diseases, the researchers said.

The new study was published in the November issue of the journal Cancer Prevention Research. The work was funded by UIC and the National Cancer Institute.  

This article was provided by MyHealthNewsDaily, a sister site to LiveScience. chronicles the daily advances and innovations made in science and technology. We take on the misconceptions that often pop up around scientific discoveries and deliver short, provocative explanations with a certain wit and style. Check out our science videos, Trivia & Quizzes and Top 10s. Join our community to debate hot-button issues like stem cells, climate change and evolution. You can also sign up for free newsletters, register for RSS feeds and get cool gadgets at the LiveScience Store.


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Please to comment
Dec 13th 2010 at 7:04 PM by honesty
Interesting article, thankyou.
Nov 28th 2010 at 10:50 PM by onqglobal
I'm in the Process of Confirming - Verifying the Truth about the 'Said' food radiation process that is said to being in usage over all American foods. This process is 'Said' to Destroy the (healthful) medicinal and the (wholesome) nutrients in both [altered] and organic produce and also processed food products. [Gives one a reasonable query to question any connections of Hidden Agenda Possibility or Probability surrounding a Full-scale organized continuous web cycle attached to the medical and food supplement industry. Which are respectively billion-to-trillion dollar gross profit environments...] The rules 'Be' a continually A-changing; that Not fair play in my book, if you will...
Nov 15th 2010 at 10:54 AM by marymusic
I'm always interested in natural health, since Nature is a healer. Thanks, Mary

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