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Health Care
marilynaliza | healthiswealth

Antibiotic for COPD

Jun 16th 2014 at 11:07 PM

Exacerbation COPD is a sudden worsening of well-being , coughing, wheezing and difficulty breathing . Exacerbations are usually caused by bacterial or viral infection. Earlier studies have suggested that this antibiotic may reduce the frequency of exacerbations of COPD, but until this study, was the first attended by patients with COPD , subjected to long-term therapy with this drug.

Participants in the study had an exacerbation in the previous year, or require oxygen therapy . 570 study participants a year, every day was getting 250 mg of azithromycin, in addition to its basic regimen.

In this group, the incidence of COPD exacerbations during the year, averaging 1.48. For comparison, 572 participants without azithromycin treatment regimen had a mean frequency of exacerbations 1.83 level.

The participants receiving azithromycin better assessed their ability to breathe and general frame of mind(Evaluation by filling out the questionnaire). The side effects of azithromycin, observed during the study were minimal.

The presence of bacteria resistant to azithromycin increased in some patients, but none of them developed symptomaticinfection
A proportion of participants receiving azithromycin, was found a slight hearing loss, which is a known side effect of the drug. Azithromycin can also cause arrhythmias in patients predisposed to cardiac arrhythmias.

Participants in the trial, there was no arrhythmia, the study did not take interest people who have an increased risk of arrhythmia. Further research is needed to determine the long-term effects of azithromycin therapy and to determine which groups of patients benefit from it the most.

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